Intractable Rare Dis Res. 2015;4(3):164. (DOI: 10.5582/irdr.2015.01020)

Electrocardiogram in anterior mid-ventricular Takotsubo syndrome variant.

Madias JE

I enjoyed reading the report by Demirelli et al., published in the May, 2015 issue of the Intractable & Rare Diseases Research, pertaining to a 59 year old woman with emotional stress-induced anterior midventricular Takotsubo syndrome (TTS) variant (1). The authors described the electrocardiogram (ECG) as showing T-wave inversions (TWI) in leads V1-V4. A recent paper reported an ECG correlate of TTS consisting of transient low voltage QRS (LVQRS) complexes (2). These ECG changes have been attributed to TTS-induced myocardial edema (ME), as detected by cardiac magnetic resonance imaging (cMRI) (2). Also TWI has been attributed to apicobasal ME gradient, as detected by cMRI (3).

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